Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice.

Cancer gene therapy - 1 Feb 2008

Curcio C, Khan A S, Amici A, Spadaro M, Quaglino E, Cavallo F, Forni G, Draghia-Akli R

Abstract excerpt

A recently developed, adaptive constant-current electroporation technique was used to immunize mice with an intramuscular injection of plasmid coding for the extracellular and transmembrane domains of the product of the rat neu(664V-E) oncogene protein. In wild-type BALB/c mice, plasmid electropo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Vaccines
Share to Electroporation
Share to Gene Transfer Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Therapy

Share to Glycoproteins

Share to Mammary Neoplasms, Experimental

Share to Receptor, ErbB-2

Share to Vaccines, DNA

Source

Identifiers

PMID: 17992201
DOI: 10.1038/sj.cgt.7701106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17992201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice.PMID 17992201Read ↗

Genetic immunization against neu/erbB2 transgenic breast cancer.Semantic proximity Read ↗

DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.Semantic proximity Read ↗

Mutational burden, MHC-I expression and immune infiltration as limiting factors for in situ vaccination by TNFα and IL-12 gene electrotransfer.Semantic proximity Read ↗

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor modelSemantic proximity Read ↗

Modeling Brain Tumors In Vivo Using Electroporation-Based Delivery of Plasmid DNA Representing Patient Mutation Signatures.Semantic proximity Read ↗

Combining Human and Rat Sequences in Her-2 DNA Vaccines Blunts Immune Tolerance and Drives Antitumor ImmunitySemantic proximity Read ↗

Recent Developments in Preclinical DNA VaccinationSemantic proximity Read ↗

Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumorsSemantic proximity Read ↗

Immunobiology of Her-2/Neu Transgenic MiceSemantic proximity Read ↗

Phase I trial of phIL12 plasmid intratumoral gene electrotransfer in patients with basal cell carcinoma in head and neck regionSemantic proximity Read ↗

DNA vaccination with a mutated p53 allele induces specific cytolytic T cells and protects against tumor cell growth and the formation of metastasis.Semantic proximity Read ↗

Identification and Characterization of the Immunodominant Rat HER-2/neu MHC Class I Epitope Presented by Spontaneous Mammary Tumors from HER-2/neu-Transgenic MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.