Article
Small Animal Jet Injection Technique Results in Enhanced Immunogenicity of Hantavirus DNA Vaccines
2020-11-09
Abstract excerpt
DNA vaccine evaluation in small animals is hampered by low immunogenicity when the vaccines are delivered using a needle and syringe. To overcome this technical hurdle we tested the possibility that a device developed for human intradermal medicine delivery might be adapted to successfully deliver a DNA vaccine to small animals. The PharmaJet ® Tropis device is a FDA 510(k)-cleared disposable syringe, needle-free...
Topics
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- Bacteriophages and microbial interactions
- Immunotherapy and Immune Responses
- Inhalation and Respiratory Drug Delivery
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- 8db4df9e-d9bf-5220-99e7-7cf4796fdac5
- DOI
- 10.1101/2020.11.09.374439
