Article
SNP selection in genome-wide association studies via penalized support vector machine with MAX test.
Computational and mathematical methods in medicine - 1 Jan 2013
Kim Jinseog, Sohn Insuk, Kim Dennis Dong Hwan, Jung Sin-Ho
Abstract excerpt
One of main objectives of a genome-wide association study (GWAS) is to develop a prediction model for a binary clinical outcome using single-nucleotide polymorphisms (SNPs) which can be used for diagnostic and prognostic purposes and for better understanding of the relationship between the disease and SNPs. Penalized support vector machine (SVM) methods have been widely used toward this end. However, since...
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