Article
Variation in vaccine response in normal populations.
Pharmacogenomics - 1 Jun 2004
Ovsyannikova Inna G, Jacobson Robert M, Poland Gregory A
Abstract excerpt
Genetic polymorphisms of the human leukocyte antigen (HLA) system significantly influence the variation in immune responses to viral vaccines. Considerable data on the genetic determinants of immune responses to the measles vaccine support the importance of HLA genes in determining the variation in vaccine response. HLA class I and class II, TAP, and HLA-DM allele associations with measles-specific antibody...
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