Article
The genetic basis for interindividual immune response variation to measles vaccine: new understanding and new vaccine approaches.
Expert review of vaccines - 1 Jan 2013
Haralambieva Iana H, Ovsyannikova Inna G, Pankratz V Shane, Kennedy Richard B, Jacobson Robert M, Poland Gregory A
Abstract excerpt
The live-attenuated measles vaccine is effective, but measles outbreaks still occur in vaccinated populations. This warrants elucidation of the determinants of measles vaccine-induced protective immunity. Interindividual variability in markers of measles vaccine-induced immunity, including neutralizing antibody levels, is regulated in part by host genetic factor variations. This review summarizes recent advances...
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