Article
Human leukocyte antigen and cytokine receptor gene polymorphisms associated with heterogeneous immune responses to mumps viral vaccine.
Pediatrics - 1 May 2008
Ovsyannikova Inna G, Jacobson Robert M, Dhiman Neelam, Vierkant Robert A, Pankratz V Shane, Poland Gregory A
Abstract excerpt
OBJECTIVES: Mumps outbreaks continue to occur throughout the world, including in highly vaccinated populations. Vaccination against mumps has been successful; however, humoral and cellular immune responses to mumps vaccines vary significantly from person to person. We set out to assess whether HLA and cytokine gene polymorphisms are associated with variations in the immune response to mumps viral vaccine....
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