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Article

Mutant fusion proteins with enhanced fusion activity promote measles virus spread in human neuronal cells and brains of suckling hamsters.

Journal of virology - 1 Mar 2013

Watanabe Shumpei, Shirogane Yuta, Suzuki Satoshi O, Ikegame Satoshi, Koga Ritsuko, Yanagi Yusuke

Abstract excerpt

Subacute sclerosing panencephalitis (SSPE) is a fatal degenerative disease caused by persistent measles virus (MV) infection in the central nervous system (CNS). From the genetic study of MV isolates obtained from SSPE patients, it is thought that defects of the matrix (M) protein play a crucial role in MV pathogenicity in the CNS. In this study, we report several notable mutations in the extracellular domain of...

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Identifiers

PMID: 23255801
DOI: 10.1128/JVI.02632-12
PMCID: PMC3571373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutant fusion proteins with enhanced fusion activity promote measles virus spread in human neuronal cells and brains of suckling hamsters.PMID 23255801Read ↗

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