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Article

Salinomycin as a Drug for Targeting Human Cancer Stem Cells

1 Jan 2012

Abstract excerpt

Cancer stem cells (CSCs) represent a subpopulation of tumor cells that possess self-renewal and tumor initiation capacity and the ability to give rise to the heterogenous lineages of malignant cells that comprise a tumor. CSCs possess multiple intrinsic mechanisms of resistance to chemotherapeutic drugs, novel tumor-targeted drugs, and radiation therapy, allowing them to survive standard cancer therapies and to...

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Identifiers

PMID: 23251084
DOI: 10.1155/2012/950658

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