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Article

Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration

27 Jan 2014

Abstract excerpt

BACKGROUND: Tumor spreading is the major threat for cancer patients. The recently published anti-cancer drug salinomycin raised hope for an improved treatment by targeting therapy-refractory cancer stem cells. However, an unambiguous role of salinomycin against cancer cell migration and metastasis formation remains elusive. FINDINGS: We report that salinomycin effectively inhibits cancer cell migration in a...

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PMID: 24468090
DOI: 10.1186/1476-4598-13-16

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