Article
Lipopolysaccharide-deficient Acinetobacter baumannii shows altered signaling through host Toll-like receptors and increased susceptibility to the host antimicrobial peptide LL-37.
Infection and immunity - 1 Mar 2013
Moffatt Jennifer H, Harper Marina, Mansell Ashley, Crane Bethany, Fitzsimons Timothy C, Nation Roger L, Li Jian, Adler Ben, Boyce John D
Abstract excerpt
Infections caused by multidrug-resistant Acinetobacter baumannii have emerged as a serious global health problem. We have shown previously that A. baumannii can become resistant to the last-line antibiotic colistin via the loss of lipopolysaccharide (LPS), including the lipid A anchor, from the outer membrane (J. H. Moffatt, M. Harper, P. Harrison, J. D. Hale, E. Vinogradov, T. Seemann, R. Henry, B. Crane, F. St....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.