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Article

Acinetobacter baumannii outer membrane vesicles elicit a potent innate immune response via membrane proteins.

PloS one - 1 Jan 2013

Jun So Hyun, Lee Jung Hwa, Kim Bo Ra, Kim Seung Il, Park Tae In, Lee Je Chul, Lee Yoo Chul

Abstract excerpt

Acinetobacter baumannii is increasingly becoming a major nosocomial pathogen. This opportunistic pathogen secretes outer membrane vesicles (OMVs) that interact with host cells. The aim of this study was to investigate the ability of A. baumannii OMVs to elicit a pro-inflammatory response in vitro and the immunopathology in response to A. baumannii OMVs in vivo. OMVs derived from A. baumannii ATCC 19606(T) induced...

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Identifiers

PMID: 23977136
DOI: 10.1371/journal.pone.0071751
PMCID: PMC3743744

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