Article
Genetic susceptibility to type 2 diabetes: a global meta-analysis studying the genetic differences in Tunisian populations.
Human biology - 1 Aug 2012
Berhouma Rym, Kouidhi Soumaya, Ammar Mariem, Abid Hafawa, Baroudi Thouraya, Ennafaa Hajer, Benammar-Elgaaied Amel
Abstract excerpt
The present study is the first meta-analysis to evaluate type 2 diabetes (T2D)- associated polymorphisms in cohorts originated from several Tunisian regions. In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNFα (-308A/G), ENPP1(K121Q), TCF7L2(rs7903146°C/T), MTHFR(C677T), ACE(I/D), and CAPN10(3R/2R)-on T2D risk, through a meta-analysis combining data of previous...
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