Genetic Variation in the Renin-Angiotensin System and Diabetic Nephropathy in the Tunisian Population.

doi:10.7754/Clin.Lab.2016.160819

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Article

Genetic Variation in the Renin-Angiotensin System and Diabetic Nephropathy in the Tunisian Population.

Clinical laboratory - 1 Mar 2017

Moussa Amira, Triki Sonia, Hamdouni Haithem, Fekih Ons, Ajmi Marwa, hajMbarek Ibtihel B, Koubaa Afifa, Neffati Fadoua, Omezzine Asma, Najjar Med-Fadhel, Bouslama Ali

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the association of ACE, angiotensinogen (AGT) and angiotensin II receptor type I (AGTR1) polymorphisms with diabetic nephropathy (DN) in Tunisians. METHODS: The study population comprised 236 type 2 diabetic patients: with nephropathy (DN = 47) and without nephropathy (DM = 189). Genotyping of ACE-I/D-rs1799752, ACE-rs4343G>A, AGT-rs5050A>C, AGT-rs 4762C>T,...

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Identifiers

PMID: 28271690
DOI: 10.7754/Clin.Lab.2016.160819

Genes

ACE
AGT
AGTR1

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