Information derived from cluster ions from DNA-modified gold nanoparticles under laser desorption/ionization: analysis of coverage, structure, and single-nucleotide polymorphism.

Abstract excerpt

In this study, we employed laser desorption/ionization mass spectrometry (LDI-MS) to explore the interactions between thiolated DNA (HS-DNA) and gold nanoparticles (Au NPs). Under nanosecond-pulsed laser irradiation (Nd:YAG, 355 nm), the efficiency of Au cluster ion formation from the Au NPs decr...

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