Article
Increased myeloid-derived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2013
Wang Linda, Chang Esther W Y, Wong Siew Cheng, Ong Siew-Min, Chong Debra Q Y, Ling Khoon Lin
Abstract excerpt
Immune dysfunction may contribute to tumor progression in gastric cancer (GC) patients. One mechanism of immune dysfunction is the suppression of T cell activation and impairment of the efficacy of cancer immunotherapy by myeloid-derived suppressor cells (MDSCs). We assessed the phenotype and imm...
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