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Article

New links to the pathogenesis of Crohn disease provided by genome-wide association scans.

Nature reviews. Genetics - 1 Jan 2008

Mathew Christopher G

Abstract excerpt

Genome-wide association scans (GWAS) using large case-control samples and several hundred thousand genetic markers have uncovered at least ten new genomic regions associated with susceptibility to Crohn disease, a chronic inflammatory bowel disorder. The new loci include genes with diverse roles in the immune response and several gene deserts, which may contain regulatory sequences or encode novel functional...

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PMID: 17968351
DOI: 10.1038/nrg2203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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