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Article

Discovering genetic variants in Crohn's disease by exploring genomic regions enriched of weak association signals.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Aug 2011

D'Addabbo Annarita, Palmieri Orazio, Maglietta Rosalia, Latiano Anna, Mukherjee Sayan, Annese Vito, Ancona Nicola

Abstract excerpt

BACKGROUND: A meta-analysis has re-analysed previous genome-wide association scanning definitively confirming eleven genes and further identifying 21 new loci. However, the identified genes/loci still explain only the minority of genetic predisposition of Crohn's disease. AIMS: To identify genes weakly involved in disease predisposition by analysing chromosomal regions enriched of single nucleotide polymorphisms...

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PMID: 21411385
DOI: 10.1016/j.dld.2011.02.010

Genes

GRB2
LCT
MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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