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Epigenome-Wide Analysis in Familial Hypercholesterolemia Identified New Loci Associated with High-Density Lipoprotein Cholesterol Concentration

1 Dec 2012

Abstract excerpt

AIM: This study aims to assess whether epigenetic changes may account for high-density lipoprotein cholesterol (HDL-C) level variability in familial hypercholesterolemia (FH), a recognized human model to study cardiovascular disease risk modulators. MATERIALS & METHODS: A genome-wide DNA methylation analysis (Infinium HumanMethylation27 BeadChip, Illumina) was performed on peripheral blood DNA samples obtained...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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PMID: 23244308
DOI: 10.2217/epi.12.62

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