Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic and genetic variations at the TNNT1 gene locus are associated with HDL-C levels and coronary artery disease.

Epigenomics - 1 Mar 2016

Guay Simon-Pierre, Légaré Cécilia, Brisson Diane, Mathieu Patrick, Bossé Yohan, Gaudet Daniel, Bouchard Luigi

Abstract excerpt

AIM: To assess whether epigenetic and genetic variations at the TNNT1 gene locus are associated with high-density lipoprotein cholesterol (HDL-C) and coronary artery disease (CAD). Patients, materials & methods: TNNT1 DNA methylation and c.-20G>A polymorphism were genotyped in subjects with and without familial hypercholesterolemia (FH). RESULTS: Lower TNNT1 DNA methylation levels were independently associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol, HDL
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Hyperlipoproteinemia Type II

Share to Polymorphism, Single Nucleotide

Share to Quebec

Share to Troponin T

Source

Identifiers

PMID: 26950807
DOI: 10.2217/epi.15.120

Genes

TNNT1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic and genetic variations at the TNNT1 gene locus are associated with HDL-C levels and coronary artery disease.PMID 26950807Read ↗

Epigenome-Wide Analysis in Familial Hypercholesterolemia Identified New Loci Associated with High-Density Lipoprotein Cholesterol ConcentrationSemantic proximity Read ↗

Association of Lipid Metabolism Related Gene Promoter Methylation with Risk of Coronary Artery DiseaseSemantic proximity Read ↗

Association of lipid metabolism-related gene promoter methylation with risk of coronary artery disease.Semantic proximity Read ↗

Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients.Semantic proximity Read ↗

ABCA1 gene promoter DNA methylation is associated with HDL particle profile and coronary artery disease in familial hypercholesterolemia.Semantic proximity Read ↗

A Preliminary Study of the Relationship between Promoter Methylation of the ABCG1, GALNT2 and HMGCR Genes and Coronary Heart DiseaseSemantic proximity Read ↗

NT5C2 Gene Polymorphisms and the Risk of Coronary Heart Disease.Semantic proximity Read ↗

Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population.Semantic proximity Read ↗

Association between global leukocyte DNA methylation and cardiovascular risk in postmenopausal women.Semantic proximity Read ↗

Coronary heart disease: NPC1L1 mutations lower CHD risk.Semantic proximity Read ↗

Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT5-8): Relationship with soluble MIF levels in coronary atherosclerotic disease subjects.Semantic proximity Read ↗

Role of genetic factors (CETP gene Taq I B polymorphism and Apo A-I gene Msp I polymorphism) in serum HDL-C levels in women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.