Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report

15 Dec 2012

Abstract excerpt

Signal transducer and activator of transcription 3 (Stat3) and Stat5 are critical signaling intermediates that promote survival in myeloid leukemias. We examined Stat3 and Stat5 activation patterns in resting and ligand-stimulated primary samples from pediatric patients with acute myeloid leukemia. Phosphorylated Stats were measured by FACS before and after stimulation with increasing doses of granulocyte-colony...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cytokine Signaling Pathways and Interactions
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23243289
DOI: 10.1182/blood-2012-04-421925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group reportPMID 23243289Read ↗

Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitorSemantic proximity Read ↗

STAT signaling in the pathogenesis and treatment of myeloid malignanciesSemantic proximity Read ↗

Integrated Clinical Genotype-Phenotype Characteristics of STAT3-Mutated Myeloid Neoplasms.Semantic proximity Read ↗

STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromesSemantic proximity Read ↗

The Role of Signal Transducer and Activator of Transcription Factors in LeukemogenesisSemantic proximity Read ↗

STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemiaSemantic proximity Read ↗

Dissecting Out a Rare Mutation, STAT: Features of STAT3-Mutant Myeloid Neoplasms.Semantic proximity Read ↗

Comprehensive analysis of expression and prognosis for signal transducer and activator of transcription family in acute myeloid leukemiaSemantic proximity Read ↗

Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote DifferentiationSemantic proximity Read ↗

Direct Targeting Options for STAT3 and STAT5 in CancerSemantic proximity Read ↗

The Stat3/5 Signaling Biosignature in Hematopoietic Stem/Progenitor Cells Predicts Response and Outcome in Myelodysplastic Syndrome Patients Treated with Azacitidine.Semantic proximity Read ↗

Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.