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Effector CD4 and CD8 T Cells and Their Role in the Tumor Microenvironment

15 Dec 2012

Abstract excerpt

T cells in tumors-the so-called tumor infiltrating lymphocytes (TIL) have been studied intensively over the past years. Compelling evidence point to a clinical relevance for high numbers of T cells at the tumor site with CD8 memory T cells as a key denominator for overall survival (OS) in patients with colo-rectal cancer (CRC), and also for others solid cancers. These data goes hand in hand with studies of...

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PMID: 23242673
DOI: 10.1007/s12307-012-0127-6

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