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Article

T lymphocyte subsets in cancer immunity: Friends or foes

2 Nov 2018

Abstract excerpt

Although immune-based therapy is proving to be a success in several cancer types, only a set of patients appear to respond to immune checkpoint blockade including PD-1 and CTLA-4. A better understanding of the crucial components of cancer immunity is therefore necessary. T lymphocytes, a key element, are found within the tumor microenvironment and seem to be critical in determining the efficacy of immune...

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PMID: 30387907
DOI: 10.1002/jlb.mr0318-097r

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