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Article

Phenotypic and spatial heterogeneity of CD8+ tumour infiltrating lymphocytes.

Molecular cancer - 9 Sept 2024

Sun Yikan, Yinwang Eloy, Wang Shengdong, Wang Zenan, Wang Fangqian, Xue Yucheng, Zhang Wenkan, Zhao Shenzhi, Mou Haochen, Chen Shixin, Jin Lingxiao, Li Binghao, Ye Zhaoming

Abstract excerpt

CD8+ T cells are the workhorses executing adaptive anti-tumour response, and targets of various cancer immunotherapies. Latest advances have unearthed the sheer heterogeneity of CD8+ tumour infiltrating lymphocytes, and made it increasingly clear that the bulk of the endogenous and therapeutically induced tumour-suppressive momentum hinges on a particular selection of CD8+ T cells with advantageous attributes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39251981
DOI: 10.1186/s12943-024-02104-w
PMCID: PMC11382426

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