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Article

Immunophenotypic and molecular features of 'cuplike' acute myeloid leukemias.

European journal of haematology - 1 Feb 2014

Carluccio Paola, Mestice Anna, Pastore Domenico, Delia Mario, Ricco Alessandra, Russo-Rossi Antonella, Casieri Paola, Liso Arcangelo, Martelli Maria Paola, Albano Francesco, Specchia Giorgina

Abstract excerpt

Nuclear invaginations, also referred to as fishmouth or cuplike nuclei, have long been identified in microgranular APL, myelomonocytic and monocytic AMLs. More recently, this typical morphological feature has been associated with NPM1 and FLT3 mutations, as well as with the lack of CD34 and HLA-D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24138595
DOI: 10.1111/ejh.12217

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24138595-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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