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Article

EGFR gene variants are associated with specific somatic aberrations in glioma.

PloS one - 1 Jan 2012

Wibom Carl, Ghasimi Soma, Van Loo Peter, Brännström Thomas, Trygg Johan, Lau Ching, Henriksson Roger, Bergenheim Tommy, Andersson Ulrika, Rydén Patrik, Melin Beatrice

Abstract excerpt

A number of gene variants have been associated with an increased risk of developing glioma. We hypothesized that the reported risk variants may be associated with tumor genomic instability. To explore potential correlations between germline risk variants and somatic genetic events, we analyzed matched tumor and blood samples from 95 glioma patients by means of SNP genotyping. The generated genotype data was used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23236348
DOI: 10.1371/journal.pone.0047929
PMCID: PMC3517607

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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