Article
Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus.
Circulation. Cardiovascular genetics - 1 Feb 2013
Divers Jasmin, Palmer Nicholette D, Lu Lingyi, Register Thomas C, Carr J Jeffrey, Hicks Pamela J, Hightower R Caresse, Smith S Carrie, Xu Jianzhao, Cox Amanda J, Hruska Keith A, Bowden Donald W, Lewis Cora E, Heiss Gerardo, Province Michael A, Borecki Ingrid B, Kerr Kathleen F, Chen Y-D Ida, Palmas Walter, Rotter Jerome I, Wassel Christina L, Bertoni Alain G, Herrington David M, Wagenknecht Lynne E, Langefeld Carl D, Freedman Barry I
Abstract excerpt
BACKGROUND: The presence and severity of coronary artery calcified plaque (CAC) differs markedly between individuals of African and European descent, suggesting that admixture mapping may be informative for identifying genetic variants associated with subclinical cardiovascular disease. METHODS AND RESULTS: Admixture mapping of CAC was performed in 1040 unrelated African Americans with type 2 diabetes mellitus...
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