Article
Interactions of the eIF-4F subunits in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry - 15 Oct 1992
Lanker S, Müller P P, Altmann M, Goyer C, Sonenberg N, Trachsel H
Abstract excerpt
Recognition of the cap structure at the 5' end of mRNA is one of the first events in initiation of eukaryotic translation. This step is mediated by the translation initiation factor 4F (eIF-4F). In mammalian cells this factor is composed of the cap-binding protein eIF-4E, eIF-4A, and a 220-kDa polypeptide. In yeast Saccharomyces cerevisiae, eIF-4E is found associated with a 150-kDa protein (p150) and a 20-kDa...
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