Article
Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.
PloS one - 1 Jan 2012
Ueki Arisa, Shimizu Takatsune, Masuda Kenta, Yamaguchi Sayaka I, Ishikawa Tomoki, Sugihara Eiji, Onishi Nobuyuki, Kuninaka Shinji, Miyoshi Keita, Muto Akihiro, Toyama Yoshiaki, Banno Kouji, Aoki Daisuke, Saya Hideyuki
Abstract excerpt
Osteosarcoma is a high-grade malignant bone tumor that manifests ingravescent clinical behavior. The intrinsic events that confer malignant properties on osteosarcoma cells have remained unclear, however. We previously established two lines of mouse osteosarcoma cells: AX cells, which are able to form tumors in syngeneic mice, and AXT cells, which were derived from such tumors and acquired an increased...
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