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Tropomodulin 3 modulates EGFR‐PI3K‐AKT signaling to drive hepatocellular carcinoma metastasis

16 Jul 2019

Abstract excerpt

The mechanism of hepatocellular carcinoma (HCC) metastasis remains poorly understood. Tropomodulin 3 (TMOD3) is a member of the pointed end capping protein family that contributes to invasion and metastasis in several types of malignancies. It has been found to be crucial for the membranous skeleton and embryonic development, although, its role in HCC progression remains largely unclear. We observed increased...

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PMID: 31313392
DOI: 10.1002/mc.23083

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