Article
Modification of the reactivity of three amino-acid residues in elongation factor 2 during its binding to ribosomes and translocation.
Biochimica et biophysica acta - 6 Apr 1990
Lavergne J P, Marzouki A, Reboud A M, Reboud J P
Abstract excerpt
The accessibility of three amino acids of EF-2, located within highly conserved regions near the N- and C-terminal extremities of the molecule (the E region and the ADPR region, respectively) to modifying enzymes has been compared within nucleotide-complexed EF-2 and ribosomal complexes that mimi...
Topics
- Adenosine Diphosphate Ribose
- Animals
- Guanine Nucleotides
- Guanosine Diphosphate
- Guanosine Triphosphate
- Liver
- Mutation
- NAD
- Peptide Elongation Factor 2
- Peptide Elongation Factors
- Peptide Mapping
- Phosphoproteins
- Phosphorylation
- Protein Binding
- Rats
- Ribosomes
- Trypsin