Article
Comparison of the Pathogenicity in Mice of A(H1N1)pdm09 Viruses Isolated between 2009 and 2015 in Japan.
Viruses - 29 Jan 2020
Mitake Hiromichi, Yasuhara Atsuhiro, Lopes Tiago J S, Tagawa-Sakai Yuko, Shimizu Kohei, Ozawa Hiroki, Kawakami Chiharu, Morikawa Saeko, Sugaya Norio, Watanabe Tokiko, Kawaoka Yoshihiro
Abstract excerpt
The A(H1N1)pdm09 virus emerged in 2009 and continues to circulate in human populations. Recent A(H1N1)pdm09 viruses, that is, A(H1N1)pdm09 viruses circulating in the post-pandemic era, can cause more or less severe infections than those caused by the initial pandemic viruses. To evaluate the changes in pathogenicity of the A(H1N1)pdm09 viruses during their continued circulation in humans, we compared the...
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