Gap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication.

Abstract excerpt

Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and has an important role in many cellular processes. Gap junction channels possess large pore allowing passage of ions and small molecules between cells. MicroRNAs (miRNAs) are small regulatory RNAs that can regulate gene expression broadly. Here, we report that miRNAs can pass through gap...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Line
• Share to Connexins
• Share to Gap Junctions