Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reciprocal expression of connexin 40 and 45 during phenotypical changes in renin-secreting cells.

American journal of physiology. Renal physiology - 1 Mar 2011

Kurt Birguel, Kurtz Lisa, Sequeira-Lopez Maria L, Gomez R Ariel, Willecke Klaus, Wagner Charlotte, Kurtz Armin

Abstract excerpt

Gap junctional coupling of renin-producing cells is of major functional importance for the control of renin synthesis and release. This study was designed to determine the relevance of the vascular gap junction protein connexin 45 (Cx45) for the control of renin expression and secretion. By crossbreeding mice which drive Cre recombinase under the control of the endogenous renin promoter with mice harboring floxed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexins
Share to Gap Junction alpha-5 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrases

Share to Lac Operon

Share to Mice, Mutant Strains

Share to Muscle, Smooth, Vascular

Share to Sodium Chloride, Dietary

Source

Open in PubMed Open full text

Identifiers

PMID: 21209011
DOI: 10.1152/ajprenal.00647.2010
PMCID: PMC3064136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reciprocal expression of connexin 40 and 45 during phenotypical changes in renin-secreting cells.PMID 21209011Read ↗

Replacement of connexin 40 by connexin 45 causes ectopic localization of renin-producing cells in the kidney but maintains in vivo control of renin gene expression.Semantic proximity Read ↗

Connexin 40 is dispensable for vascular renin cell recruitment but is indispensable for vascular baroreceptor control of renin secretion.Semantic proximity Read ↗

The connexin 40 A96S mutation causes renin-dependent hypertension.Semantic proximity Read ↗

The renin phenotype: roles and regulation in the kidney.Semantic proximity Read ↗

Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened.Semantic proximity Read ↗

Transcriptional regulator RBP-J regulates the number and plasticity of renin cells.Semantic proximity Read ↗

Connexin43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts.Semantic proximity Read ↗

Cells of renin lineage are adult pluripotent progenitors in experimental glomerular disease.Semantic proximity Read ↗

Ablation of renin-expressing juxtaglomerular cells results in a distinct kidney phenotype.Semantic proximity Read ↗

Gene targeting in physiological investigations: studies of the renin-angiotensin system.Semantic proximity Read ↗

Cells of renin lineage take on a podocyte phenotype in aging nephropathy.Semantic proximity Read ↗

Synthesis and secretion of renin in mice with induced genetic mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.