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Article

Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain).

Autophagy - 1 Jan 2018

Latomanski Eleanor A, Newton Hayley J

Abstract excerpt

Coxiella burnetii is an intracellular bacterial pathogen which causes Q fever, a human infection with the ability to cause chronic disease with potentially life-threatening outcomes. In humans, Coxiella infects alveolar macrophages where it replicates to high numbers in a unique, pathogen-directed lysosome-derived vacuole. This compartment, termed the Coxiella-containing vacuole (CCV), has a low internal pH and...

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Identifiers

PMID: 29973118
DOI: 10.1080/15548627.2018.1483806
PMCID: PMC6135622

Genes

CLTC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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