Article
Influence of the functional polymorphisms in the organic anion transporting polypeptide 1B1 in the susceptibility to colorectal cancer.
Genetic testing and molecular biomarkers - 1 Mar 2013
Ozhan Gül, Kara Mehtap, Sari Fatih M, Yanar Hakan T, Alpertunga Buket
Abstract excerpt
Colorectal cancer is an important cause of death throughout the world, and its etiology involves the interaction of genetic and environmental factors. Transporter proteins are important in protecting organs from xenobiotics or toxins. Organic anion-transporting polypeptide 1B1 (OATP1B1) plays role in hepatic uptake and clearance of albumin-bound amphipathic organic compounds, including endogen substances, drugs,...
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