Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks

19 Feb 2010

Abstract excerpt

BACKGROUND: An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in various human tumors. To reveal the molecular machinery underlying the stem-like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Liver physiology and pathology
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20167130
DOI: 10.1186/1476-4598-9-39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarksPMID 20167130Read ↗

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cellsSemantic proximity Read ↗

CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicitySemantic proximity Read ↗

Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviiiSemantic proximity Read ↗

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cellsSemantic proximity Read ↗

CREB5 promotes the proliferation and self-renewal ability of glioma stem cellsSemantic proximity Read ↗

Characteristics of CD133 <sup>+</sup> Human Colon Cancer SW620 CellsSemantic proximity Read ↗

Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.Semantic proximity Read ↗

GSTT1 mediates stemness and FGFR inhibitor sensitivity in pancreatic cancer through regulation of CD133 ( <i>PROM1</i> )Semantic proximity Read ↗

SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1Semantic proximity Read ↗

Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2Semantic proximity Read ↗

Hypoxia-Inducible Factors Activate CD133 Promoter through ETS Family Transcription FactorsSemantic proximity Read ↗

Molecular characterization of CD133+ cancer stem-like cells in endometrial cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.