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Article

Genetic variants in brain-derived neurotrophic factor associated with Alzheimer's disease.

Journal of medical genetics - 1 Feb 2007

Huang R, Huang J, Cathcart H, Smith S, Poduslo S E

Abstract excerpt

BACKGROUND: Alzheimer's disease is complex, with variants in multiple genes contributing to interactions increasing risk for the disease. Brain-derived neurotrophic factor (BDNF) promotes neuronal survival and modulates hippocampal-dependent memory. METHODS: We examined 11 SNPs that spanned the gene on chromosome 11p14 in 220 Alzheimer's patients and 128 control spouses. RESULTS: Not all of the SNPs were...

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Identifiers

PMID: 17293537
DOI: 10.1136/jmg.2006.044883
PMCID: PMC2598055

Genes

APOE
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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