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Article

MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.

The Journal of biological chemistry - 18 Jan 2013

Venkataraman Sujatha, Birks Diane K, Balakrishnan Ilango, Alimova Irina, Harris Peter S, Patel Purvi R, Handler Michael H, Dubuc Adrian, Taylor Michael D, Foreman Nicholas K, Vibhakar Rajeev

Abstract excerpt

Aberrant expression of microRNAs has been implicated in many cancers. We recently demonstrated differential expression of several microRNAs in medulloblastoma. In this study, the regulation and function of microRNA 218 (miR-218), which is significantly underexpressed in medulloblastoma, was evalu...

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Identifiers

PMID: 23212916
DOI: 10.1074/jbc.M112.396762
PMCID: PMC3548500

Genes

CDK6
CTSB
REST
RICTOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23212916-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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