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Article

miR-489 inhibits proliferation, cell cycle progression and induces apoptosis of glioma cells via targeting SPIN1-mediated PI3K/AKT pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Sept 2017

Li Yan, Ma Xiaolin, Wang Yanpeng, Li Guohua

Abstract excerpt

microRNA-489 (miR-489), a newly identified tumor-related miRNA, functions as an oncogene or tumor suppressor via regulating growth and metastasis of human cancers. But, the clinical significance, biological function and underlying mechanisms of miR-489 in glioma remain rarely known. Here, we showed that the levels of miR-489 in glioma tissues were notably underexpressed compared to corresponding non-tumor...

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Source

Identifiers

PMID: 28666210
DOI: 10.1016/j.biopha.2017.06.058

Genes

SPIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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