Article

MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting Nuclear Factor I/B (NFIB)

2021-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Medulloblastoma (MB), the most frequent malignant pediatric brain tumor, is subdivided into four primary subgroups, wingless-type (WNT), sonic hedgehog (SHH), group 3, and group 4. Haploinsufficiency of chromosome 17p13.3 and c-Myc amplification distinguish high-risk group 3 tumors associated with rapid metastasis, recurrence and early mortality. We sought to identify the ro...

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Literature Corpus work: 1ebeb3d8-c0bb-5e17-a56e-77492c2a248d
DOI: 10.1101/2021.04.15.440074

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