Article
Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype.
Cancer research - 15 Jan 2013
Ying Zhe, Li Yun, Wu Jueheng, Zhu Xun, Yang Yi, Tian Han, Li Wei, Hu Bo, Cheng Shi-Yuan, Li Mengfeng
Abstract excerpt
Phenotypic similarities have long been recognized between subpopulations of glioma and neural stem cells. Many of these similar properties, including the robust abilities to self-renew, migrate, and invade, are hallmarks of glioma cells that render them extremely aggressive. However, the molecular mechanisms underlying this character, particularly in glioma stem-like cells that drive this disease, remain poorly...
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