Article
Correlation between beta-lipoprotein levels and outcome of hepatitis C treatment.
Hepatology (Baltimore, Md.) - 1 Aug 2006
Gopal Kavitha, Johnson Timothy C, Gopal Saraswathi, Walfish Aaron, Bang Christine T, Suwandhi Pauline, Pena-Sahdala Helene N, Clain David J, Bodenheimer Henry C, Min Albert D
Abstract excerpt
The low-density lipoprotein receptor (LDLR) has been proposed as a candidate receptor for the hepatitis C virus (HCV). Competitive inhibition of HCV binding to the LDLR by low-density lipoprotein (LDL) has been shown in vitro. If similar inhibition occurs in vivo, an elevated serum concentration of beta-lipoproteins may reduce the efficiency of infecting hepatocytes with HCV by competitively inhibiting HCV viral...
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