Article
[Molecular genetic basis of age-related macular degeneration].
Vestnik oftalmologii - 1 Jan 2000
Boĭko É V, Churashov S V, Kamilova T A
Abstract excerpt
Visual loss due to age-related macular degeneration (AMD) is caused by one or both forms of advanced disease: "wet" (neovascular) or "dry" (geographic atrophy). Immune system plays a central role in pathogenesis and progression of both AMD forms. Main genetic polymorphisms associated with risk of AMD development and progression were found to be genes that regulate inflammation especially in complement factor H...
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