Article
Interaction of an S100A9 gene variant with saturated fat and carbohydrates to modulate insulin resistance in 3 populations of different ancestries.
The American journal of clinical nutrition - 1 Aug 2016
Blanco-Rojo Ruth, Delgado-Lista Javier, Lee Yu-Chi, Lai Chao-Qiang, Perez-Martinez Pablo, Rangel-Zuñiga Oriol, Smith Caren E, Hidalgo Bertha, Alcala-Diaz Juan F, Gomez-Delgado Francisco, Parnell Laurence D, Arnett Donna K, Tucker Katherine L, Lopez-Miranda Jose, Ordovas Jose M
Abstract excerpt
BACKGROUND: S100 calcium-binding protein A9 (S100A9) has previously been identified as a type 2 diabetes (T2D) gene. However, this finding requires independent validation and more in-depth analyses in other populations and ancestries. OBJECTIVES: We aimed to replicate the associations between an S100A9 variant and insulin resistance and T2D and to initiate an investigation of potential interactions with the...
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