Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin-like Growth Factor 2 mRNA-Binding Protein 2—a Potential Link Between Type 2 Diabetes Mellitus and Cancer

1 Jun 2021

Abstract excerpt

CONTEXT: Type 2 diabetes mellitus (T2DM) and cancer share a variety of risk factors and pathophysiological features. It is becoming increasingly accepted that the 2 diseases are related, and that T2DM increases the risk of certain malignancies. OBJECTIVE: This review summarizes recent advancements in the elucidation of functions of insulin-like growth factor 2 (IGF-2) messenger RNA (mRNA)-binding protein 2...

Topics

Join the communities discussing this publication.

Genetic Syndromes and Imprinting
Growth Hormone and Insulin-like Growth Factors
Metabolism, Diabetes, and Cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34061963
DOI: 10.1210/clinem/dgab391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-like Growth Factor 2 mRNA-Binding Protein 2—a Potential Link Between Type 2 Diabetes Mellitus and CancerPMID 34061963Read ↗

Insulin resistance and cancer: the role of insulin and IGFsSemantic proximity Read ↗

Non-Coding RNAs in IGF-1R Signaling Regulation: The Underlying Pathophysiological Link between Diabetes and CancerSemantic proximity Read ↗

The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility.Semantic proximity Read ↗

Quantitative assessment of the variation in IGF2BP2 gene and type 2 diabetes risk.Semantic proximity Read ↗

Replication of association study between type 2 diabetes mellitus and IGF2BP2 in Han Chinese population.Semantic proximity Read ↗

IGF2BP2 genetic variation and type 2 diabetes: a global meta-analysis.Semantic proximity Read ↗

Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathwaySemantic proximity Read ↗

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.Semantic proximity Read ↗

IGF2BP2 and IGF2 genetic effects in diabetes and diabetic nephropathy.Semantic proximity Read ↗

IGF2BP2 and obesity interaction analysis for type 2 diabetes mellitus in Chinese Han population.Semantic proximity Read ↗

Differentially expressed IGF2BP2 in ovarian disorders: strongly associates with alternative splicing regulation in human granulosa cellsSemantic proximity Read ↗

THE RELEVANCE OF RS6777038 AND RS6444082 OF IGF2BP2 GENE POLYMORPHISM AND TYPE 2 DIABETES MELLITUS: A CASE CONTROL STUDY.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.