Article
Multiple promoters and targeted microRNAs direct the expressions of HMGB3 gene transcripts in dairy cattle.
Animal genetics - 1 Jun 2013
Li Liming, Huang Jinming, Ju Zhihua, Li Qiuling, Wang Changfa, Qi Chao, Zhang Yan, Hou Qinlei, Hang Suqin, Zhong Jifeng
Abstract excerpt
HMGB3 (high-mobility group box 3) is an X-linked member of a family of sequence-independent chromatin-binding proteins and functions as a universal sentinel for nucleic acid-mediated innate immune responses. The splice variant expression, promoter characterization and targeted microRNAs of the bovine HMGB3 gene were investigated to explore its expression pattern and possible regulatory mechanism. The results...
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