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Article

Cyclophilin Inhibitors: An Emerging Class of Therapeutics for the Treatment of Chronic Hepatitis C Infection

29 Oct 2012

Abstract excerpt

The advent of the replicon system together with advances in cell culture have contributed significantly to our understanding of the function of virally-encoded structural and nonstructural proteins in the replication cycle of the hepatitis C virus. In addition, in vitro systems have been used to identify several host proteins whose expression is critical for supporting such diverse activities as viral entry, RNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23202494
DOI: 10.3390/v4112558

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