Article
New targets for antiviral therapy of chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2012
Bühler Sandra, Bartenschlager Ralf
Abstract excerpt
Until recently, chronic hepatitis C caused by persistent infection with the hepatitis C virus (HCV) has been treated with a combination of pegylated interferon-alpha (PEG-IFNα) and ribavirin (RBV). This situation has changed with the development of two drugs targeting the NS3/4A protease, approved for combination therapy with PEG-IFNα/RBV for patients infected with genotype 1 viruses. Moreover, two additional...
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