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Article

In brief: BRCA1 and BRCA2.

The Journal of pathology - 1 Aug 2013

Foulkes William D, Shuen Andrew Y

Abstract excerpt

The discovery of the first major breast cancer susceptibility gene, BRCA1, occurred almost 20 years ago. BRCA1, together with BRCA2 remain the most important discoveries in human cancer genetics. Identification of highly penetrant mutations in these two tumour suppressor genes has had broad implications for women at risk and their families, for health professionals caring for these persons and for basic...

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Source

Identifiers

PMID: 23620175
DOI: 10.1002/path.4205

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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