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Article

The role of Nanog expression in tamoxifen-resistant breast cancer cells

1 Jun 2015

Abstract excerpt

There is an accumulation of evidence that shows a significant role of cancer stem cells in tumor initiation, proliferation, relapse, and metastasis. Nanog is the most important core transcription marker of stem cells, known by its role in maintaining pluripotency, proliferation, and differentiation. Therefore, this study aimed to examine the role of Nanog in breast cancer cell tamoxifen resistance and its...

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PMID: 26082649
DOI: 10.2147/ott.s67835

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